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Nitrendipine impurity

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SL-4660

Nitrendipine impurity, >98%

CAS No. : [89267-43-6]

IUPAC Name : 5-(Ethoxycarbonyl)-2-(hydroxymethyl)-6-methyl-4-(3-nitrophenyl)nicotinic acid

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Chemical Properites
Mol. Formula :
C17H16N2O7
Mol. Weight :
360.32
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Nitrendipine, which is a dihydropyridine calcium channel blocker. It is used in the treatment of primary hypertension to decrease blood pressure and can reduce the cardiotoxicity of cocaine.

References : Bean B. P. Proc Natl Acad Sci U S A, 81(20), 6388-92, 1984; Peterson B. Z. etal.: J. Biol. Chem. 271(10), 5293-6, 1996; Bellemann P. et al. Arzneimittelforschung 31(12), 2064-7, 1981; Bolger G. T. et al.: J. Pharmacol Exp Ther., 225(2), 291-309, 1983.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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