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NLRP3 inhibitor

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SI-7450

NLRP3 inhibitor, >98% (HPLC)

CAS No. : [2927413-30-5]

IUPAC Name : N-(5-Chloro-2-(2-Methoxyethoxy)benzyl)-N-(5-(N-propylsulfamoyl)-2,3-dihydro-1H-inden-2-yl)benzofuran-2-carboxamide

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C31H33ClN2O6S
Mol. Weight :
597.12
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a potent NLRP3 inhibitor (IC50 = 0.13 μM) used in DSS‑colitis models to study inflammasome‑driven inflammation.

References : Sun S. et al.: J. Med. Chem., 66(23), 16141-16167, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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