NMDA receptor antagonist

SI-7615

NMDA receptor antagonist, >98% (HPLC)

IUPAC Name : (S)-3-(3-(4-(7-Chloro-1H-indole-2-carbonyl)piperazin-1-yl)propyl)isobenzofuran-1(3H)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This is a GluN2B‑selective NMDA receptor antagonist with strong functional potency (IC₅₀ ≈ 74 nM), excellent subtype selectivity, good brain exposure, and in vivo anti‑stroke efficacy comparable to Ifenprodil. Its favorable safety profile supports as a promising preclinical anti‑stroke candidate.

References : Lin G. et al.: J. Med. Chem., 67(5), 3358-3384, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.