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NMS-P715

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SI-4110

NMS-P715, >98% (HPLC)

CAS No. : [1202055-32-0]

MDL No. : MFCD19443684

IUPAC Name : N-(2,6-Diethylphenyl)-1-methyl-8-((4-((1-methylpiperidin-4-yl)carbamoyl)-2-(trifluoromethoxy)phenyl)amino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide

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Chemical Properites
Mol. Formula :
C35H39F3N8O3
Mol. Weight :
676.73
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : NMS-P715 is a selective, ATP-competitive inhibitor of MPS1, with an IC50 of 182 nM.

References : Liu Y. et al.: J. Med. Chem., 58(8), 3366-3392, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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