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NO-Aspirin

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SL-983

NO-Aspirin, >98%

CAS No. : [287118-97-2]

MDL No. : MFCD08062164

Synonyms : NCX-4040

IUPAC Name : 4-((Nitrooxy)methyl)phenyl 2-acetoxybenzoate

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MG95.00
Back Order  Estimated to ship on 20 September 2026
10MG155.00
Back Order  Estimated to ship on 20 September 2026
25MG295.00
Back Order  Estimated to ship on 20 September 2026
50MG355.00
Back Order  Estimated to ship on 20 September 2026
250MG995.00
Back Order  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C16H13NO7
Mol. Weight :
331.28
Appearance :
Pale yellow solid
Melting Point :
84-86oC (lit.)
For Laboratory research use only, not for drug, household or other uses.

Applications : NO-Aspirin is a nitric oxide-donating form of aspirin. NCX-4040 inhibits cyclooxygenase activity and releases NO, which can down-regulate COX2 expression and reduce the levels of superoxide accumulation. In the human monocytic cell line THP1, the compound inhibits PGE2 production and cytokine expression, and appears to stabilize IkB by inhibiting proteasome function. NCX-4040 has been shown to induce apoptosis in several tumour cell lines.

References : Tesei A. et al.: Journal of Translational Medicine, 3(1), 7, 2005; Anna Tesei A et al.: Journal of Translational Medicine, 5, 52, 2007; Marvasi M. et al.: AMB Express, 6(1), 49,2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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