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CAS No. : [287118-97-2]
MDL No. : MFCD08062164
Synonyms : NCX-4040
IUPAC Name : 4-((Nitrooxy)methyl)phenyl 2-acetoxybenzoate
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | 95.00 | Back Order | Estimated to ship on 20 September 2026 | |
| 10MG | 155.00 | Back Order | Estimated to ship on 20 September 2026 | |
| 25MG | 295.00 | Back Order | Estimated to ship on 20 September 2026 | |
| 50MG | 355.00 | Back Order | Estimated to ship on 20 September 2026 | |
| 250MG | 995.00 | Back Order | Estimated to ship on 20 September 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C16H13NO7 | Mol. Weight : 331.28 |
Appearance : Pale yellow solid | Melting Point : 84-86oC (lit.) |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : NO-Aspirin is a nitric oxide-donating form of aspirin. NCX-4040 inhibits cyclooxygenase activity and releases NO, which can down-regulate COX2 expression and reduce the levels of superoxide accumulation. In the human monocytic cell line THP1, the compound inhibits PGE2 production and cytokine expression, and appears to stabilize IkB by inhibiting proteasome function. NCX-4040 has been shown to induce apoptosis in several tumour cell lines.
References : Tesei A. et al.: Journal of Translational Medicine, 3(1), 7, 2005; Anna Tesei A et al.: Journal of Translational Medicine, 5, 52, 2007; Marvasi M. et al.: AMB Express, 6(1), 49,2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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