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non‑SAM‑like inhibitor

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SI-8058

non‑SAM‑like inhibitor, >98% (HPLC)

IUPAC Name : N-(3-(4-(6-Chloro-2-oxoindolin-3-yl)piperidin-1-yl)-3-oxopropyl)acrylamide

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C19H22ClN3O3
Mol. Weight :
375.85
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a potent non‑SAM‑like inhibitor of SARS‑CoV‑2 Nsp14 (IC50= 32 µM) , the SAM‑dependent N7‑guanine methyltransferase required for viral RNA capping and immune evasion.

References : Singh I. et al.: J. Med. Chem., 66(12), 7785-7803, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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