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Non‑Tubulin‑targeting oxazole derivative 2

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SI-7310

Non‑Tubulin‑targeting oxazole derivative 2, >98% (HPLC)

IUPAC Name : 2-Methoxy-5-((7-(3,4,5-trimethoxyphenyl)-5,6-dihydropyrrolo[3',4':3,4]cyclohepta[1,2-d]isoxazol-8(4H)-yl)methyl)aniline

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Chemical Properites
Mol. Formula :
C27H29N3O5
Mol. Weight :
475.55
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a pyrrolo‑cyclohepta‑oxazole derivative showing broad sub‑micromolar antiproliferative activity across four non‑Hodgkin lymphoma cell lines, with VL51 sensitivity at 0.10 μM. It displays high selectivity for cancer cells and low toxicity toward human peripheral blood lymphocytes, supporting its potential as a promising lead for lymphoma therapy.

References : Barreca M. et al.: European Journal of Medicinal Chemistry, Volume 254, 115372, 5 June 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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