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Nonivamide-d3

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SL-1202

Nonivamide-d3, >98% (CP)

Isotopic Purity : 99 atom % D

Related CAS No. : [2444-46-4] of the unlabelled compound

Synonyms : Nonylic vanillamide-d3; Pelargonic acid vanillylamide-d3; Pseudocapsaicin-d3

IUPAC Name : N-(4-Hydroxy-3-(methoxy-d3)benzyl)nonanamide

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Chemical Properites
Mol. Formula :
C17H24D3NO3
Mol. Weight :
296.42
Appearance :
Solid
Melting Point :
57-58oC (lit.)
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version of Nonivamide, which is is a naturally occuring analog of Capsaicin (SL-391) isolated from peppers, described to produce effects similar to Capsaicin as an agonist of the VR1 (TRPV1 receptor. Nonivamide is demonstrated to stimulate afferent neurons with about half the potency of Capsaicin. Agonism of the VR1 (TRPV1) receptor by Nonivamide was demonstrated to induce the release of Ca2+ from the endoplasmic reticulum (ER) of human lung cells, producing ER stress and cell death. This can be used as an internal reference standard.

References : Kozukue N. et al.: J. Ag. Food Chem., 53, 9172, 2005; Choi S. et al.: J. Ag. Food Chem., 54, 9224, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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