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Norcapsaicin-d3

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Norcapsaicin-d3, >98% (CP)

Isotopic Purity : Isotopic Purity: 99 atom % D

Related CAS No. : [61229-08-1] of the unlabelled compound

IUPAC Name : (E)-N-(4-Hydroxy-3-methoxy-d3 benzyl)-7-methyloct-5-enamide

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C17H22D3NO3
Mol. Weight :
294.40
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version of Norcapsaicin and an analog of Capsaicin, which is the principal pungent component in hot peppers, including red chilli peppers, and it has a profound antiproliferative effect on prostate cancer cells, inducing the apoptosis of both androgen receptor (AR)-positive (LNCaP) and -negative (PC-3, DU-145) prostate cancer cell lines associated with an increase of p53, p21, and Bax.Capsaicin inhibited NF-kappa activation by preventing its nuclear migration. This can be used as an internal reference standard.

References : Mori A. et al.: Cancer Res., 66(6), 3222,2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : Highly Irritant and Lachrymator! In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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