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Nortadalafil

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SL-2412

Nortadalafil, >98%

CAS No. : [171596-36-4]

MDL No. : MFCD19443817

Synonyms : Demethyl tadalafil

IUPAC Name : (6R,12aR)-6-(Benzo[d][1,3]dioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
1G10.00
Back Order  Estimated to ship on 04 October 2026
5G30.00
Back Order  Estimated to ship on 04 October 2026
25G95.00
Back Order  Estimated to ship on 04 October 2026
100G295.00
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C21H17N3O4
Mol. Weight :
375.38
Appearance :
White solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Nortadalafil is demethyl Tadalafil, which is a PDE5 inhibitor, currently marketed in pill form for treating erectile dysfunction (ED) under the name Cialis; and under the name Adcirca for the treatment of pulmonary arterial hypertension.

References : Beghyn T. et al.: Bioorganic & Medicinal Chemistry Letters, 17(3), 789-792, 2007; Daugan A. et al.: Journal of Medicinal Chemistry 46(21), 4533-4542, 2003; Porst H. et al.: Expert Opin Pharmacother. 13(10), 1481-1494, 2012; Frey M. K et al.: Expert Opin Pharmacother.,13(5), 747-755, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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