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NVP-2

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SI-5947

NVP-2, >98% (HPLC)

CAS No. : [1263373-43-8]

MDL No. : MFCD28385769

IUPAC Name : 4-(((5'-Chloro-2'-(((1R,4r)-4-(((R)-1-methoxypropan-2-yl)amino)cyclohexyl)amino)-[2,4'-bipyridin]-6-yl)amino)methyl)tetrahydro-2H-pyran-4-carbonitrile

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Chemical Properites
Mol. Formula :
C27H37ClN6O2
Mol. Weight :
513.08
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : NVP-2 is a potent, selective, non-neurotoxic and ATP-competitive cyclin dependent kinase 9 (CDK9) inhibitor in the development of potential cancer therapy agent.

References : Olson M. C. et al.: Nat Chem Biol., 14(2), 163-170, 2018; Winter G. E. et al.: Mol Cell 67(1), 5-18 e19, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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