NVP-AEW-541

SI-6455

NVP-AEW-541, >98% (HPLC)

CAS No. : [475489-16-8]

Synonyms : AEW-541

IUPAC Name : 7-((1s,3s)-3-(Azetidin-1-ylmethyl)cyclobutyl)-5-(3-(benzyloxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : NVP‑AEW-541 potently inhibits IGF‑1R (IC₅₀ = 0.15 µM) and InsR (IC₅₀ = 0.14 µM), providing effective blockade of growth‑factor signaling pathways. It displays notable antitumor activity and is widely used in studies of IGF‑driven oncogenesis.

References : García-Echeverría C. et al.: Cancer Cell., 5(3), 231-9, 2004; Tanno B. et al.: Clin. Cancer Res.,12(22), 6772-6780, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.