NVP-AEW-541 dihydrochloride

SI-6456

NVP-AEW-541 dihydrochloride, >98% (HPLC)

CAS No. : [2320261-63-8]

Synonyms : AEW-541 dihydrochloride

IUPAC Name : 7-((1s,3s)-3-(Azetidin-1-ylmethyl)cyclobutyl)-5-(3-(benzyloxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine dihydrochloride

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25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : NVP‑AEW-541 dihydrochloride potently inhibits IGF‑1R (IC₅₀ = 0.15 µM) and InsR (IC₅₀ = 0.14 µM), providing effective blockade of growth‑factor–driven signaling pathways. It shows notable antitumor activity and is widely used in studies of IGF‑dependent oncogenesis.

References : García-Echeverría C. et al.: Cancer Cell, 5(3), 231-9, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.