NVP-CLR 457

SI-7092

NVP-CLR 457, >98% (HPLC)

CAS No. : [1453082-52-4]

IUPAC Name : (4S,5R)-3-(2'-Amino-2-morpholino-4'-(trifluoromethyl)-[4,5'-bipyrimidin]-6-yl)-4-(hydroxymethyl)-5-methyloxazolidin-2-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : NVP‑CLR457 functions as an orally active and highly potent pan‑class I PI3K inhibitor, exhibiting balanced isoform inhibition and a well‑defined dose‑dependent PK/PD/efficacy profile. It demonstrates strong antitumor effects.

References : Fairhurst R. A. et al.: J. Med. Chem., 65(12), 8345-8379, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.