NVP-DFV-890

SI-7356

NVP-DFV-890, >98% (HPLC)

CAS No. : [2271394-34-2]

Synonyms : NLRP3 antagonist 2

IUPAC Name : (R)-N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-2-(2-hydroxypropan-2-yl)thiazole-5-sulfonimidamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : NVP‑DFV-890 selectively targets NLRP3 through direct binding, inhibiting ATPase‑dependent activation, cytokine maturation, and pyroptotic cell death. Its ability to promote early SARS‑CoV‑2 clearance highlights its relevance for mechanistic and therapeutic research in COVID‑19 pneumonia and coronavirus‑associated acute respiratory distress syndrome.

References : Madurka I. et al.: Infection, 51(3), 641-654, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.