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NX-1607

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SI-7540

NX-1607, >98% (HPLC)

CAS No. : [2573775-59-2]

Synonyms : Cbl-b-IN-3

IUPAC Name : 2-(3-((1s,3R)-3-Methyl-1-(4-methyl-4H-1,2,4-triazol-3-yl)cyclobutyl)phenyl)-6-(((S)-3-methylpiperidin-1-yl)methyl)-4-(trifluoromethyl)isoindolin-1-one

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Chemical Properites
Mol. Formula :
C30H34F3N5O
Mol. Weight :
537.63
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : NX‑1607 potently inhibits the E3 ligase Cbl‑b (IC50 < 1 nM), a key suppressor of T‑cell activation and antitumor immunity. Its pharmacological profile supports its use in studies of cancer biology and immune‑modulatory mechanisms.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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