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O-Desethyl resiquimod

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SL-9836

O-Desethyl resiquimod, >98%

CAS No. : [144875-23-0]

IUPAC Name : 1-(4-Amino-2-(hydroxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol

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Chemical Properites
Mol. Formula :
C15H18N4O2
Mol. Weight :
286.33
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a metabolite or analog of Resiquimod, which is an immune response modifier that acts as a potent TLR 7/8 agonist. Resiquimod is used to treat viral skin lesions and certain types of skin cancer, such as early-stage cutaneous T-cell lymphoma (CTCL) and melanoma.

References : Hemmi H. et al.: Nat Immunol., 3(2), 196-200, 2002; Loré K. et al.: J. Immunol., 171(8), 4320-4328, 2003; Lee M. et al. Arch Pharm Res., 37(9), 1234-1240, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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