O-Deshydroxyethyl bosentan

SL-2587

O-Deshydroxyethyl bosentan, >98% (HPLC)

CAS No. : [174227-14-6]

MDL No. : MFCD25977341

Synonyms : Bosentan USP related compound B

IUPAC Name : 4-(tert-Butyl)-N-(6-hydroxy-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide

Price And Availability
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10MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
100MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
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Applications : O-Deshydroxyethyl bosentan is a metabolite of Bosentan, which is a competitive and dual antagonist of endothelin-1 (ET) for the ET_A and ET_B receptors.

References : Dhillon S. et al.: Am J. Cardiovasc Drugs 9(5), 331-350, 2009; Akamata K. et al.: Arthritis Res Ther. 16(2), R86, 2014; Iglarz M. et al.: Life Sci. 118(2), 333-339, 2014; Son G. Y. et al.: PLoS One 11(12), e0167713, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.