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O-Desmethyl mycophenolate mofetil ether

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SL-3573

O-Desmethyl mycophenolate mofetil ether, >98%

Synonyms : O-Desmethyl mycophenolate ether

IUPAC Name : 2-Morpholinoethyl 3-(5-hydroxy-2,6-dimethyl-9-oxo-3,4,7,9-tetrahydro-2H-furo[3,4-h]chromen-2-yl)propanoate

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Chemical Properites
Mol. Formula :
C22H29NO7
Mol. Weight :
419.47
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : O-Desmethyl mycophenolate mofetil ether is an impurity of Mycophenolate mofetil, which is a prodrug of Mycophenolic acid. A potent IMPDH inhibitor and the active metabolite of an immunosuppressive drug, used to prevent rejection in organ transplantation.

References : Nakanishi T. et al.: Int Immunopharmacol.,10(1), 91-97, 2010; Dehghani F. et al.: Neuropathol Appl Neurobiol., 36(7), 598-611, 2010; Ozgen M. et al.: Clin Exp Dermatol., 37(1), 48-54, 2012; Ebrahimi F. et al.: J. Neuroinflammation 9(1), 89, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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