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CAS No. : [301693-28-7]
Synonyms : Polmacoxib impurity 6
IUPAC Name : 4-(4-(2-Fluorophenyl)-2,2-dimethyl-5-oxo-2,5-dihydrofuran-3-yl)benzenesulfonamide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 10MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 25MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 50MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 100MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C18H16FNO4S | Mol. Weight : 361.39 |
Appearance : Pale beige solid | Melting Point : Not available |
Solubility : MeOH | |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : This is an impurity of Polmacoxib, which is an orally administered nonsteroidal anti-inflammatory drug (NSAID) that acts as a dual inhibitor of COX-2 and carbonic anhydrase. It is indicated for managing pain and inflammation related to osteoarthritis of the hip and knee. Additionally, Polmacoxib has been shown to inhibit colorectal adenoma and tumor growth in mouse models.
References : Kim S. H. et al.: Invest New Drugs 32(6), 1105-1112, 2014; Flick C. A. et al.: J. Med. Chem., 60(15), 6480-6515, 2017.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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