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O6-3-(Aminomethyl)benzyl]guanine

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O6-3-(Aminomethyl)benzyl]guanine, >98%

CAS No. : [948903-72-8]

MDL No. : MFCD11655596

IUPAC Name : 6-(3-(Aminomethyl)benzyloxy)-9H-purin-2-amine

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
25MG995.00
In Stock  Estimated to ship on 20 September 2026
100MG2995.00
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C13H14N6O
Mol. Weight :
270.29
Appearance :
White solid
Melting Point :
158-160oC (dec.)
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : O6-[3-(Aminomethyl)benzyl]guanine is the analog of O6-[4-(aminomethyl)benzyl]guanine, potential intermediate for the synthesis of suitable O6-alkylguanine-DNA alkyltransferase inhibitor and found that the substitution of aminomethyl at the meta-position greatly enhances inactivation of alkyltransferase.

References : Pauly. G. T. et. al.: J. Med. Chem.,51,7144, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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