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O6-[4-(13-Azido-2,5,8,11-tetraoxa-tridecyl)benzyl]guanine

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SL-1116

O6-[4-(13-Azido-2,5,8,11-tetraoxa-tridecyl)benzyl]guanine, >96%

CAS No. : [680622-75-7]

MDL No. : MFCD30146060

IUPAC Name : 6-[4-(13-azido-2,5,8,11-tetraoxatridecyl)benzyloxy]-9H-purin-2-amine

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Chemical Properites
Mol. Formula :
C21H28N8O5
Mol. Weight :
472.51
Appearance :
Oily liquid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : It is a benzylguanine PEG-azide analog, a useful precursor for covalent and irreversible dimerization of fusion proteins of O6-alkylguanine-DNA alkyltransferase (AGT or SNAP-Tag) in vitro and in living cells. The cross-linking efficiency of AGT fusion proteins provides a measure to characterize the proximity and interactions of protein pairs in living cells.

References : Guillaume L. et al.: Angew. Chem. Ed., 46(23), 4281, 2007.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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