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O6-Benzylguanine

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O6-Benzylguanine, >98%

CAS No. : [19916-73-5]

MDL No. : MFCD00269931

IUPAC Name : 2-Amino-6-(phenylmethoxy)-9H-purine

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5G10.00
In Stock  Estimated to ship on 20 September 2026
25G15.00
In Stock  Estimated to ship on 20 September 2026
100G40.00
In Stock  Estimated to ship on 20 September 2026
500G195.00
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C12H11N5O
Mol. Weight :
241.25
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : O(6)-Benzylguanine is an irreversible inactivator of O(6)-alkylguanine-DNA alkyltransferase currently in clinical trials to overcome alkyltransferase-mediated resistance to certain cancer chemotherapeutic alkylating agents.

References : Pauly.G. T. et. al.: J. Med. Chem., 51(22), 7144, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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