Obatoclax mesylate

SI-7922

Obatoclax mesylate, >98% (HPLC)

CAS No. : [803712-79-0]

Synonyms : GX-15-070 mesylate

IUPAC Name : (E)-2-(2-((3,5-Dimethyl-1H-pyrrol-2-yl)methylene)-3-methoxy-2H-pyrrol-5-yl)-1H-indole methanesulfonate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Obatoclax mesylate inhibits multiple anti‑apoptotic BCL‑2 family proteins, showing a K_i of 220 nM for BCL‑2. It induces autophagy‑mediated cell death and promotes cyclin D1 degradation via the proteasome. Its combined anti‑cancer and antiparasitic properties support its use across diverse biological and therapeutic studies.

References : Or C. R. et al.: Int . J. Mol. Sci., 18(1), 2016; Nguyen M. et al.: Proc. Natl. Acad. Sci. U S A, 104(49), 19512-7, 2007; Sulkshane P. et al.: Oncotarget, 8(36), 60060-60079, 2016; Ehrenkaufer G. et al.: PLoS Negl. Trop. Dis., 14(3), e0008150, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.