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Obeticholic acid methyl ester

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Obeticholic acid methyl ester, >98%

CAS No. : [951694-73-8]

IUPAC Name : 1-((2'-(2-((2S,3S,4S,5R,6R)-6-Carboxy-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
100MG165.00
In Stock  Estimated to ship on 20 September 2026
500MG695.00
In Stock  Estimated to ship on 20 September 2026
1G1355.00
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C27H46O4
Mol. Weight :
434.65
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Obeticholic acid methyl ester is a bile acid analog of Obeticholic acid, which is a potent and selective FXR agonist (EC50=99 nM) endowed with anticholestatic activity.

References : Fiorucci S. et al.: J. Pharmacol Exp Ther., 313(2), 604-612, 2005; Ghebremariam Y. T. et al.: PLoS One 8(4), e60653, 2013; Verbeke L. et al.: Am J. Pathol., 185(2), 409-419, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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