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Obicetrapib

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SI-6777

Obicetrapib, >98% (HPLC)

CAS No. : [866399-87-3]

Synonyms : TA-8995; DEZ-001; AMG-899

IUPAC Name : 4-((2-((3,5-Bis(trifluoromethyl)benzyl)((2R,4S)-1-(ethoxycarbonyl)-2-ethyl-6-(trifluoromethyl)-1,2,3,4-tetrahydroquinolin-4-yl)amino)pyrimidin-5-yl)oxy)butanoic acid

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Chemical Properites
Mol. Formula :
C32H31F9N4O5
Mol. Weight :
722.61
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Obicetrapib is an orally active CETP inhibitor that robustly decreases LDL‑C, ApoB, and Lp(a) and increases HDL‑C. Its lipid‑modulating profile makes it a valuable tool for investigating dyslipidemia and ASCVD mechanisms.

References : Ford J. et al.: Br. J. Clin. Pharmacol., 78(3), 498-508, 2014; Hovingh G. K. et al.: Lancet., 386(9992), 452-60, 2015; Nicholls S. J. et al.: Nat. Med., 28(8), 1672-1678, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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