Ocifisertib

SI-8024

Ocifisertib, >98% (HPLC)

CAS No. : [1338806-73-7]

Synonyms : CFI-400945 free base

IUPAC Name : (1R,2S)-2-(3-((E)-4-(((2S,6R)-2,6-Dimethylmorpholino)methyl)styryl)-1H-indazol-6-yl)-5'-methoxyspiro[cyclopropane-1,3'-indolin]-2'-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : CFI‑400945 free base is an orally active PLK4 inhibitor characterized by exceptional potency (K_i = 0.26 nM; IC₅₀ = 2.8 nM). Its high selectivity and strong target engagement make it a valuable tool for probing PLK4‑dependent signaling pathways.

References : Sampson P. B. et al.: J. Med. Chem., 58(1), 147-69, 2015; Mason J. M. et al.: Cancer Cell, 26(2), 163-76, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.