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CAS No. : [2387510-88-3]
IUPAC Name : (13Z,15E)-25-Chloro-14,15-dihydro-3,6-dioxa-9-aza-1(3,5)-pyrazolo[1,5-a]pyrimidina-2(1,3)-benzenacyclononaphane hydrochloride
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C16H15ClN4O2 • HCl | Mol. Weight : 367.23 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : OD-36 hydrochloride potently inhibits RIPK2 and features a macrocyclic scaffold that enables strong interaction with the ALK2 ATP pocket. Its ALK2‑directed activity (K_D = 37 nM) supports its use in studies of RIPK2 signaling and ALK2‑dependent biological processes.
References : Tigno-Aranjuez J. T. et al.: J. Biol. Chem., 289(43), 29651-64, 2014; Sanchez-Duffhues G. et al.: J. B. M. R. Plus., 3(11), e10230, 2019; Tigno-Aranjuez J. T. et al.: J. Biol. Chem., 289(43), 29651-64, 2014.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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