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Odanacatib

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SI-5315

Odanacatib, >98% (HPLC)

CAS No. : [603139-19-1]

MDL No. : MFCD11042419

Synonyms : MK-0822

IUPAC Name : (S)-N-(1-Cyanocyclopropyl)-4-fluoro-4-methyl-2-(((S)-2,2,2-trifluoro-1-(4'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)ethyl)amino)pentanamide

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Chemical Properites
Mol. Formula :
C25H27F4N3O3S
Mol. Weight :
525.56
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Odanacatib is a potent and selective inhibitor of cathepsin K, with an IC50 of 0.2 nM for human cathepsin K.

References : Yves Gauthier. J. et al.: Bioorg Med Chem Lett.,18(3), 923-928, 2008; Leung P. et al.: Bone 49(4), 623-635, 2011; Ng K. W. Clin Interv Aging. 7, 235-47, 2012; Yi C. et al.: Sci Rep. 7, 44682, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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