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OL-1

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SI-6434

OL-1, >98% (HPLC)

IUPAC Name : (E)-2-(11-(3-(Dimethylamino)propylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetohydrazide

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C21H25N3O2
Mol. Weight :
351.45
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : OL‑1 is a potent PARP inhibitor, targeting PARP‑dependent DNA repair and inducing synthetic lethality in DNA‑repair‑deficient cancer cells. It serves as a tool compound for studying PARP‑mediated DNA damage responses and evaluating PARP‑targeted therapeutic strategies.

References : Liao M. et al.: J. Med. Chem., 64(5), 2382-2418, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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