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Olafertinib

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SI-7834

Olafertinib, >98% (HPLC)

CAS No. : [1660963-42-7]

Synonyms : CK-101; RX-518

IUPAC Name : N-(3-(2-((2,3-Difluoro-4-(4-(2-hydroxyethyl)piperazin-1-yl)phenyl)amino)quinazolin-8-yl)phenyl)acrylamide

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C29H28F2N6O
Mol. Weight :
530.58
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Olafertinib is an irreversible, orally active third‑generation EGFR inhibitor with strong selectivity for EGFR‑sensitizing and resistance mutations and limited activity against wild‑type EGFR. This profile makes it a valuable tool for investigating EGFR‑mutant NSCLC and other EGFR‑dependent malignancies.

References : Johnson M. et al.: Journal of Thoracic Oncology, 13(10), S323, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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