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Olmesartan-d4 EP impurity A

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Olmesartan-d4 EP impurity A, >99% (HPLC)

Isotopic Purity : 98 atom % D

CAS No. : [1420880-41-6]

Synonyms : Olmesartan-d4 acid

IUPAC Name : 1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid-d4

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Chemical Properites
Mol. Formula :
C24H22D4N6O3
Mol. Weight :
450.53
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version an impurity of Olmesartan medoxomil, which is a selective angiotensin II type 1 (AT(1)) receptor antagonist, used in the treatment of high blood pressure.

References : Kurikawa N. et al.: Br. J. Pharmacol.,139(6), 1085-1094, 2003; Koike H. et al.: J. Hypertens Suppl., 9(1), S3-14, 2001; Nagib M. M. et al.: Toxicol Appl Pharmacol., 271(1), 106-113, 2013; Nakamoto T. et al.: Eur. J. Pharmacol., 528(1-3), 43-51, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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