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Olmesatran impurity E

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Olmesatran impurity E, >98%

CAS No. : [1418133-31-9]

Synonyms : Olmesatran medoxomil impurity 17

IUPAC Name : 2-(1-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-5-(((5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy)carbonyl)-2-propyl-1H-imidazol-4-yl)propan-2-yl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylate

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Chemical Properites
Mol. Formula :
C53H54N12O8
Mol. Weight :
987.09
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Olmesartan, which is a selective angiotensin II type 1 (AT(1)) receptor antagonist, used in the treatment of high blood pressure.

References : Kurikawa N. et al.: Br. J. Pharmacol.,139(6), 1085-1094, 2003; Koike H. et al.: J. Hypertens Suppl., 9(1), S3-14, 2001; Nagib M. M. et al.: Toxicol Appl Pharmacol., 271(1), 106-113, 2013; Nakamoto T. et al.: Eur. J. Pharmacol., 528(1-3), 43-51, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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