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Olopatadine-d3 hydrochloride

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SL-8609

Olopatadine-d3 hydrochloride, >98%

CAS No. : [1331635-21-2]

Synonyms : ALO4943A-d3; KW4679-d3

IUPAC Name : (Z)-2-(11-(3-(Methyl(methyl-d3)amino)propylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetic acid hydrochloride

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Chemical Properites
Mol. Formula :
C21H20D3NO3 . HCl
Mol. Weight :
376.90
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version of Olopatadine hydrochloride, which is an orally active and selective histamine 1 (H1) receptor antagonist and a mast cell stabilizer. Olopatadine hydrochloride prevents immunologically stimulated pro-inflammatory mediator release from human conjunctival mast cells. Olopatadine hydrochloride can be used for researching allergic conjunctivitis.

References : Kam K. W. et al.: Ocul Immunol Inflamm., 25(5), 663-677, 2017; Leonardi A. et al.: Expert Opin Pharmacother., 11(6), 969-81, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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