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Olutasidenib

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SI-5700

Olutasidenib, >98% (HPLC)

CAS No. : [1887014-12-1]

Synonyms : FT-2102

IUPAC Name : (S)-5-((1-(6-Chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2-carbonitrile

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Chemical Properites
Mol. Formula :
C18H15ClN4O2
Mol. Weight :
354.79
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Olutasidenib is a potent, orally bioavailable, brain penetrant and selective mutant IDH1 (mIDH1) inhibitor, developing for the potential traetment of acute myeloid leukemia (AML).

References : Caravella J. A. et al.: J. Med Chem., 63(4), 1612-1623, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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