OM-153

SI-7071

OM-153, >98% (HPLC)

CAS No. : [2406278-81-5]

IUPAC Name : N-((1R,3r)-3-(5-(5-Ethoxypyridin-2-yl)-4-(2-fluorophenyl)-4H-1,2,4-triazol-3-yl)cyclobutyl)quinoxaline-5-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : OM‑153 potently inhibits TNKS1/2 with low‑nanomolar activity and blocks Wnt/β‑catenin signaling (reporter IC₅₀ = 0.63 nM). In COLO 320DM cells, it reduces pathway activation and proliferation, highlighting its utility in Wnt‑driven cancer research.

References :
Leenders R. G. G. et al.: J. Med. Chem., 64(24), 17936-17949, 2021; Shoshy A. Brinch et al.: Cancer Research Communications, 2(4), 233-245, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.