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Omipalisib

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SI-5333

Omipalisib, >98% (HPLC)

CAS No. : [1086062-66-9]

MDL No. : MFCD16038929

Synonyms : GSK2126458; GSK458

IUPAC Name : 2,4-Difluoro-N-(2-methoxy-5-(4-(pyridazin-4-yl)quinolin-6-yl)pyridin-3-yl)benzenesulfonamide

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Chemical Properites
Mol. Formula :
C25H17F2N5O3S
Mol. Weight :
505.50
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Omipalisib is a potent and selective inhibitor of the PI3K/mammalian target of rapamycin (mTOR) pathway. Omipalisib has anti-cancer activity.

References : Knight S. D. et al.: ACS Med. Chem. Lett., 1 (1), 39-43, 2010; Greger J. G. et al.: Mol Cancer Ther., 11(4), 909-20, 2012; Kim H. G. et al.: ACS Chem Biol., 8(10), 2145-50, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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