ON-108600

SI-6919

ON-108600, >98% (HPLC)

CAS No. : [1585246-23-6]

IUPAC Name : (Z)-6-((2,6-Dichlorobenzyl)sulfonyl)-2-(4-hydroxy-3-nitrobenzylidene)-2H-benzo[b][1,4]thiazin-3(4H)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : ON-108600 potently inhibits CK2, TNIK, and DYRK1 kinases, showing sub‑micromolar IC₅₀ values across DYRK1A/B, DYRK2, CK2α1/α2, and TNIK. This multi‑kinase activity contributes to its strong antitumor effects in preclinical models.

References : Katsutoshi S. et al.: Nat. Commun., 12(1), 4671, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.