Onalespib

SI-5755

Onalespib, >98% (HPLC)

CAS No. : [912999-49-6]

MDL No. : MFCD18633198

Synonyms : AT13387

IUPAC Name : (2,4-Dihydroxy-5-isopropylphenyl)(5-((4-methylpiperazin-1-yl)methyl)isoindolin-2-yl)methanone

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Onalespib is a long-acting second-generation Hsp90 inhibitor with a Kd of 0.71 nM. Onalespib inhibits tumor growth and has the potential to improve radiotherapy outcomes, prolonging the overall survival of cancer patients.

References : Woodhead A. J. et al.: J. Med. Chem., 53(16), 5956-69, 2010; Kang M. H. et al.: Pediatr Blood Cancer., 59(1), 185-8, 2012; Spiegelberg D. et al.: Scientific Reports 10, Article No.5923, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.