Onfasprodil

SI-7622

Onfasprodil, >98% (HPLC)

CAS No. : [1892581-29-1]

Synonyms : MIJ-821

IUPAC Name : 6-((S)-2-((3aR,5R,6aS)-5-(2-Fluorophenoxy)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-1-hydroxyethyl)pyridin-3-ol

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Onfasprodil selectively inhibits NR2B‑subunit NMDA receptors through negative allosteric modulation and is delivered intravenously. It elicits rapid antidepressant‑like responses and is widely used in studies exploring NMDA‑based mechanisms in treatment‑resistant depression.

References : Gomez-Mancilla B. et al.: Clin. Transl. Sci., 16(11), 2236-2252, 2023; Shelton R. C. et al.: J. Clin. Psychiatry., 86(3), 23m15246, 2025.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.