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ONO-4578

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SI-7083

ONO-4578, >98% (HPLC)

CAS No. : [1965316-82-8]

Synonyms : EP4 receptor antagonist 2

IUPAC Name : 4-(4-Cyano-2-((2'R,4S)-6-(isopropylcarbamoyl)spiro[chromane-4,1'-cyclopropane]-2'-carboxamido)phenyl)butanoic acid

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Chemical Properites
Mol. Formula :
C27H29N3O5
Mol. Weight :
475.55
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : ONO-4578 features a tricyclic spiro‑based scaffold and selectively targets the EP4 receptor. It displays notable microsomal stability, making it a useful tool compound for probing EP4‑mediated pathways.

References : Tohru K. et al.: Cancer Res., 80(16), 4443, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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