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Orforglipron imidazole (R)-isomer impurity

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Orforglipron imidazole (R)-isomer impurity, >98%

IUPAC Name : (R)-1-(4-Fluoro-1-methyl-1H-indazol-5-yl)-3-(2-(4-fluoro-3,5-dimethylphenyl)-4-methyl-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridin-3-yl)-1,3-dihydro-2H-imidazol-2-one

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C26H25F2N7O
Mol. Weight :
489.53
Appearance :
Pale beige solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Orforglipron, which is a novel non-peptidyl oral glucagon-like peptide-1 (GLP-1) receptor agonist, developming for treatment of type 2 diabetes mellitus (T2DM).

References : Cong Z. et al.: Nat Commun., 12(1), 3763, 2021; Choe H. J. et al.: Endocrinol Metab (Seoul) 36(1), 22-29, 2021; Kawai T. et al.: Proc Natl Acad Sci U S A. 17(47), 29959-29967, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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