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Osimertinib impurity A

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SL-3716

Osimertinib impurity A, >98%

CAS No. : [1421373-98-9]

Synonyms : AZ-5104

IUPAC Name : N-(5-((4-(1H-Indol-3-yl)pyrimidin-2-yl)amino)-2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxyphenyl)acrylamide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
100MG195.00
Back Order  Estimated to ship on 04 October 2026
250MG335.00
Back Order  Estimated to ship on 04 October 2026
1G1195.00
Back Order  Estimated to ship on 04 October 2026
We accept
Chemical Properites
Mol. Formula :
C27H31N7O2
Mol. Weight :
485.58
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Osimertinib (Osimertinib impurity A), which is a third-generation epidermal growth factor receptor (EGFR) inhibitor, used to treat non-small-cell lung carcinomas with a specific mutation.

References : Finlay M. R. et al. J. Med Chem., 57(20), 8249-8267, 2014; Cross D. A. et al.: Cancer Discov., 4(9), 1046-1061, 2014; Eberlein C. A. et al.: Cancer Res., 75(12), 2489-2500, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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