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Oteseconazole

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SL-11184

Oteseconazole, >98%

CAS No. : [1340593-59-0]

Synonyms : VT-1161

IUPAC Name : (R)-2-(2,4-Difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol

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25MGRequest A Quote
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Chemical Properites
Mol. Formula :
C23H16F7N5O2
Mol. Weight :
527.4
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Oteseconazole is a potent, orally active antifungal agent. It exhibits strong affinity for and inhibition of Candida albicans cytochrome P45051 (CYP51) activity (Kd ≤39 nM), while demonstrating no significant effect on human CYP51. Additionally, Oteseconazole may be utilized in research involving dermatophytes.

References : Warrilow A. G. et al.: Antimicrob Agents Chemother., 58(12), 7121-7, 2014; Garvey E. P. et al.: Antimicrob Agents Chemother., 59(4), 1992-7, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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