OTS-964 hydrochloride

SI-7807

OTS-964 hydrochloride, >98% (HPLC)

CAS No. : [1338545-07-5]

IUPAC Name : (R)-9-(4-(1-(Dimethylamino)propan-2-yl)phenyl)-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one hydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : OTS-964 hydrochloride selectively inhibits TOPK with low‑nanomolar potency (IC₅₀= 28 nM) and also binds CDK11B with high affinity (Kd = 40 nM). Its combined TOPK and CDK11 inhibitory profile makes it a valuable tool for probing mitotic regulation and transcription‑associated kinase signaling in cancer models.

References : Matsuo Y. et al.: Sci. Transl. Med., 6(259), 259ra145, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.