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Oxo enzalutamide

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Oxo enzalutamide, >98%

CAS No. : [1242137-18-3]

Synonyms : Enzalutamide impurity 4; Oxo-MDV 3100

IUPAC Name : 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide

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Chemical Properites
Mol. Formula :
C21H16F4N4O3
Mol. Weight :
448.37
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : Oxo enzalutamide is an impurity of Enzalutamide (Enzalutamide impurity 4), which is an androgen-receptor (AR) antagonist for the treatment for prostate cancer.

References : Tran C. et al.: Science, 324(5928), 787-790, 2009; Scher H. I. et al.: Lancet.,375(9724), 1437-1446, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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