p38-alpha MAPK-IN-5

SI-7854

p38-α MAPK-IN-5, >98% (HPLC)

CAS No. : [1443242-46-3]

IUPAC Name : 1-(3-(tert-Butyl)-1'-(2-(dimethylamino)ethyl)-1'H-[1,4'-bipyrazol]-5-yl)-3-((1S,4R)-4-((3-((S)-2-methylpiperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridin-6-yl)oxy)-1,2,3,4-tetrahydronaphthalen-1-yl)urea

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This is a nanomolar‑potency p38α inhibitor with pronounced isoform selectivity, inhibiting p38α and p38β far more strongly than p38γ or p38δ. Its robust anti‑inflammatory activity supports its use in mechanistic and pharmacological studies of airway inflammatory diseases, including asthma and COPD.

References : Armani E. et al.: J. Med. Chem., 65(10), 7170-7192, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.