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Paclitaxel-d5

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SL-4333

Paclitaxel-d5, >98% (HPLC)

Isotopic Purity : 98 atom % D

CAS No. : [1129540-33-5]

Synonyms : NSC-125973-d5; Taxol-d5

IUPAC Name : (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-9-(((2R,3S)-3-(Benzamido-2,3,4,5,6-d5)-2-hydroxy-3-phenylpropanoyl)oxy)-12-(benzoyloxy)-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-3,4,4a,5,6,9,10,11,12,12a-decahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-6,12b(2aH)-diyl diacetate

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C47H46D5NO14
Mol. Weight :
858.95
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Paclitaxel-d5 is a deuterium labelled version of Paclitaxel, which is a naturally occurring antineoplastic agent and stabilizes tubulin polymerization. Paclitaxel can cause both mitotic arrest and apoptotic cell death. Tubulin depolymerization inhibitor. It is used to treat a number of types of cancers.This includes ovarian cancer, breast cancer, lung cancer, Kaposi sarcoma, cervical cancer, and pancreatic cancer.

References : Wang J. et al.: Anticancer Drugs., 14(1), 13-19, 2003; Sun R. G et al.: Gen Physiol Biophys, 31(1), 1-10,2012; Zhang X. H. et al.: Cancer Lett., 322(2), 213-222, 2012; Chang J. et al. Breast Cancer Res Treat.. 134(3), 969-80, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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