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Palbociclib glycosamine

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Palbociclib glycosamine, >98%

IUPAC Name : 6-Acetyl-8-cyclopentyl-2-((5-(4-((3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)piperazin-1-yl)pyridin-2-yl)amino)-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one

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5MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C36H49N7O12
Mol. Weight :
771.83
Appearance :
Yellow solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a glycosamine analog of Palbociclib, which is a selective CDK4 and CDK6 inhibitor. Palbociclib is used for the treatment of ER-positive and HER2-negative breast cancer.

References : Fry D. W. et al.: Mol Cancer Ther., 3(11), 1427-1438, 2004; Katsumi Y. et al.: Biochem Biophys Res Commun, 413(1), 62-68, 2011; Goel S. et al.: Nature 548(7668), 471-475, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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