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Palbociclib hydrochloride

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SI-1599

Palbociclib hydrochloride, >98%

CAS No. : [827022-32-2]

MDL No. : MFCD22420809

IUPAC Name : 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MG55.00
In Stock  Estimated to ship on 20 September 2026
10MG80.00
In Stock  Estimated to ship on 20 September 2026
50MG95.00
In Stock  Estimated to ship on 20 September 2026
100MG125.00
In Stock  Estimated to ship on 20 September 2026
500MG295.00
In Stock  Estimated to ship on 20 September 2026
We accept
Chemical Properites
Mol. Formula :
C24H29N7O2 . HCl
Mol. Weight :
483.99
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Palbociclib hydrochloride is a selective CDK4 and CDK6 inhibitor with IC50s of 11 and 16 nM, respectively. Palbociclib is a drug for the treatment of ER-positive and HER2-negative breast cancer.

References : Fry D. W. et al.: Mol Cancer Ther., 3(11), 1427-1438, 2004; Katsumi Y. et al.: Biochem Biophys Res Commun., 413(1), 62-68,2011; Goel S. et al.: Nature 548(7668), 471-475, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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